What is USBVaccine.exe?

The .exe extension on a filename indicates an executable file. Executable files may, in some cases, harm your computer. Therefore, please read below to decide for yourself whether the USBVaccine.exe on your computer is a Trojan that you should remove, or whether it is a file belonging to the Windows operating system or to a trusted application.

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USBVaccine.exe file information

Windows Task Manager with USBVaccine
USBVaccine.exe process in Windows Task Manager

The process known as USB Vaccine belongs to software Panda USB Vaccine by Panda Security (

Description: USBVaccine.exe is not essential for the Windows OS and causes relatively few problems. The file USBVaccine.exe is located in a subfolder of "C:\Program Files". Known file sizes on Windows 10/8/7/XP are 1,287,176 bytes (66% of all occurrences), 1,268,808 bytes or 412,928 bytes. 
USBVaccine.exe is a Verisign signed file. The USBVaccine.exe file is digitally signed. USBVaccine.exe is not a Windows core file. The program is not visible. USBVaccine.exe is able to record keyboard and mouse inputs. Therefore the technical security rating is 32% dangerous.

Uninstalling this variant: The software vendor offers the option to ask for help from Support, search for an update on the vendor’s website or uninstall Panda USB Vaccine from your computer using the Control Panel applet Uninstall a Program.

Recommended: Identify USBVaccine.exe related errors

Important: Some malware camouflages itself as USBVaccine.exe, particularly when located in the C:\Windows or C:\Windows\System32 folder. Therefore, you should check the USBVaccine.exe process on your PC to see if it is a threat. We recommend Security Task Manager for verifying your computer's security. This was one of the Top Download Picks of The Washington Post and PC World.


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Best practices for resolving USBVaccine issues

A clean and tidy computer is the key requirement for avoiding problems with USBVaccine. This means running a scan for malware, cleaning your hard drive using cleanmgr and sfc /scannow, uninstalling programs that you no longer need, checking for Autostart programs (using msconfig) and enabling Windows' Automatic Update. Always remember to perform periodic backups, or at least to set restore points.

Should you experience an actual problem, try to recall the last thing you did, or the last thing you installed before the problem appeared for the first time. Use the resmon command to identify the processes that are causing your problem. Even for serious problems, rather than reinstalling Windows, you are better off repairing of your installation or, for Windows 8 and later versions, executing the DISM.exe /Online /Cleanup-image /Restorehealth command. This allows you to repair the operating system without losing data.

To help you analyze the USBVaccine.exe process on your computer, the following programs have proven to be helpful: Security Task Manager displays all running Windows tasks, including embedded hidden processes, such as keyboard and browser monitoring or Autostart entries. A unique security risk rating indicates the likelihood of the process being potential spyware, malware or a Trojan. Malwarebytes Anti-Malware detects and removes sleeping spyware, adware, Trojans, keyloggers, malware and trackers from your hard drive.

Other processes

USBVaccine.exe [all]